Renal Disease: Drug Dosing and Drug-Induced Nephrotoxicity

Websites:    

Clinical Practice Guidelines

• Canadian Diabetes Association 2008 Clinical Practice Guidelines
• Canadian Society of Nephrology Hemodialysis Clinical Practice Guidelines (2006) - see Chapter 3: Mineral Metabolism
• Canadian Society of Nephrology Clinical Practice Guidelines for the Management of Anemia Associated with Chronic Kidney Disease (2008)
• Guidelines for the management of chronic kidney disease (PDF) (CMAJ, 2008)
• National Kidney Foundation Kidney Disease Outcomes Quality Initiative (NKF KDOQI)
• National Kidney Foundation KDOQI Guidelines and Commentaries

Websites for Health Professionals

2010 Dialysis of Drugs (PDF)
• Chronic Kidney Disease Resource Center (Medscape, registration required)
• Cochrane Renal Reviews (Cochrane Renal Group)
• Hypertension, Dialysis and Clinical Nephrology
• National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
• National Kidney and Urologic Diseases Information Clearinghouse (NKUDIC)
• National Kidney Foundation
• Renal Pharmacists Network

• Canadian Diabetes Association
• International Society for Peritoneal Dialysis
• Kidney Foundation of Canada
• National Kidney Foundation

Drug Dosing in Renal Disease

• Creatinine Clearance Dosage Adjustment for Varying Degrees of Renal Dysfunction of Common Drugs (University of Arkansas for Medical Sciences, Pharmacy Services)
• Drug Dosing Adjustments in Patients with Chronic Kidney Disease
•  Drug Prescribing in Renal Failure: Dosing Guidelines for Adults and Children (5th ed. 2007) - $
• Guidelines for Antibiotic Use: Antibiotic Dosing in Renal Impairment (University of Pennsylvania Medical Center)
•  The Renal Drug Handbook (Ashley & Currie, 3rd ed. 2009) - $
• WHO Model Formulary 2008 (PDF) - see Appendix IV: Renal Impairment
  

links to electronic resources accessible online for Dal-affiliated persons

• Cockcroft-Gault Calculator (with SI Units)
• GFR Calculators (National Kidney Disease Education Program)
• MDRD GFR Calculator (with SI Units)

Renal Patient Resources

• Diabetes and Kidney Disease (Canadian Diabetes Association)
• Kidney Foundation of Canada  
• National Kidney Foundation
• Patient Resources (Renal Pharmacists Network)

• Dialysis Statistics (Canadian Institute for Health Information)

Infectious Disease

• Dialysis Event (Centers for Disease Control and Prevention)
• Guidelines for Vaccinating Kidney Dialysis Patients & Patients with Chronic Kidney Disease (PDF) (Centers for Disease Control and Prevention)

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Patient Decision Aids:    

• Patient Decision Aids (Ottawa Hospital Research Institute)
• Patient Decision Aids (National Prescribing Centre)

Recommended texts & electronic resources are linked to publishers' or book sellers'    websites for further ordering information:

• Applied Therapeutics: The Clinical Use of Drugs (Koda-Kimble et al. 9th ed. 2008) - see Chapter 34: Dosing of Drugs in Renal Failure - $
•  Brenner and Rector's The Kidney (8th ed. 2008) - see Chapter 57: Prescribing Drugs in Kidney Disease - $
•  Clinical Nephrotoxins: Renal Injury From Drugs and Chemicals (Broe & Porter, 3rd ed. 2008) - $
•  Drug Prescribing in Renal Failure: Dosing Guidelines for Adults and Children (Brier & Aronoff, 5th ed. 2007) - $
• Introduction to Renal Therapeutics (Ashley & Morlidge, 2008) - $
•  Pharmacotherapy: A Pathophysiologic Approach (DiPiro et al. 7th ed. 2008) - see Chapter 49: Drug-Induced Kidney Disease and Chapter 51: Drug Therapy Individualization for Patients with Renal Insufficiency - $
• Pharmacotherapy: A Pathophysiologic Approach (DiPiro et al. 8th ed. 2011)
• Primer on Kidney Diseases (Greenberg, 5th ed. 2009) - see Chapter 34: Kidney Failure Due to Therapeutic Agents, Chapter 39: Analgesics and the Kidney and Chapter 40: Principles of Drug Therapy in Kidney Failure - $
• Seldin and Giebisch's The Kidney: Physiology & Pathophysiology (Alpern & Hebert, 4th ed. 2007) - see Chapter 87: Cellular Mechanisms of Drug Nephrotoxicity, Chapter 98: Disposition and Dose Requirements of Drugs in Renal Insufficiency, Chapter 101: Cellular Mechanism of Drug Nephrotoxicity and Chapter 104: Disposition and Dose Requirements of Drugs in Renal Insufficiency - $
• Textbook of Therapeutics: Drug and Disease Management (Helms & Quan, 8th ed. 2006) - see Chapter 44: Dialysis Options and Pharmacotherapy for End-Stage Renal Disease - $
• The Merck Manual of Diagnosis and Therapy (18th ed. 2006, also available online) - see Chapter 226: Toxic Nephrology
•  Therapeutic Choices (Carol/Repchinsky, 6th ed. 2011) - $
  

links to electronic resources accessible online for Dal-affiliated persons

• Citations in which Kidney/drug effects OR Kidney Diseases/chemically induced (as major concepts) are combined with Drug Therapy/adverse effects OR Pharmaceutical Preparations/adverse effects (as major concepts) using AND.
• Practice guidelines that include information on Kidney Diseases/chemically induced.
• All reviews that include information on Kidney Diseases/chemically induced as a major concept and limited to Humans.
• Systematic reviews that include information on Kidney Diseases/chemically induced.

• Follow this link to search PubMed for the latest citations in which Kidney Failure as a major concept is combined using AND with Pharmaceutical Preparations/administration and dosage – the results limited to Humans.